Drug
This page outlines the Site of Care for Specialty Drug Administration policy and the medications to which this policy applies. It provides the criteria used to determine the medical necessity of hospital outpatient administration as the site of service for identified specialty medications (See Site of Care for Specialty Drug Infusion/Injection applicable drug therapy below.)
Site of care
The starting dose(s) of the medications subject to this policy may be given at the physician’s facility of choice only when multiple administrations are required and provided that the medication is available and not subject to limited distribution. For identified gene and cellular therapies, all doses (including the starting dose(s)) must be administered at an Aetna Institutes® Gene Based, Cellular and Other Innovative Therapy (GCIT®) Network listed in the policy apply (See GCIT Designated Centers below.)
This includes hospital outpatient facilities, non-hospital outpatient facilities and home care. In the event the therapy is represented by a single administration, the policy applies to the first administration.
All subsequent doses will be subject to the Aetna Site of Care for Drug Administration policy, which requires the use of non-hospital outpatient facilities or home care.
Clinical rationale and documentation must be provided for review of Medical Necessity exceptions. (See Criteria for Medical Necessity below.)
Site of care for specialty drug infusion/Injection applicable drug therapy
Actemra IV formulation – effective 1/1/2019
Adakveo – effective 2/13/2020
Aduhelm – effective 8/3/2021
Aldurazyme – effective 1/1/2020
Alpha 1 proteinase inhibitors (Glassia, Prolastin C, Aralast NP, Zemaira) – effective 1/1/2020
Amondys 45 – effective 6/1/2021
Amvuttra – effective 9/22/2022
Avsola (infliximab-axxq) – effective 9/1/2020
Bavencio – effective 7/1/2020
Benlysta IV formulation – effective 7/1/2019
Briumvi – effective 4/11/2023
Cerezyme – effective 1/1/2020
Cinqair – effective 9/1/2020
Cinryze – effective 1/1/2020
Crysvita – effective 7/13/2018
Elaprase – effective 1/1/2020
Elelyso – effective 1/1/2020
Entyvio – effective 1/1/2019
Evkeeza – effective 5/7/21
Exondys 51 – effective 1/11/2017
Fabrazyme – effective 1/1/2020
Fasenra (provider-administered) – effective 9/1/2020
Givlaari – effective 2/13/2020
HemgenixGCIT – effective 3/17/2023
Imfinzi – effective 7/1/2020
Immune Globulins – effective 1/1/2017
Inflectra (infliximab-dyyb) – effective 7/1/2017
Jemperli – effective 7/1/2021
Kanuma – effective 1/1/2020
Keytruda – effective 7/1/2020
Lemtrada – effective 7/1/2017
Leqembi – effective 04/5/2023
Libtayo – effective 7/1/2020
Lumizyme – effective 1/1/2020
LuxturnaGCIT – effective 3/9/2018
Mepsevii – effective 1/1/2020
Naglazyme – effective 1/1/2020
Nexviazyme – effective 10/7/2021
Nucala (provider-administered) – effective 9/1/2020
Ocrevus – effective 05/23/2017
Onpattro – effective 08/23/2018
Orencia IV formulation – effective 1/1/2019
Oxlumo – effective 3/17/2021
Radicava (edaravone IV) – effective 7/20/2017
Remicade (infliximab) – effective 7/1/2017
Renflexis (infliximab-abda) – effective 9/1/2017
Saphnelo – effective 10/7/2021
Simponi Aria – effective 1/1/2019
SkysonaGCIT – effective 1/1/2023
Soliris – effective 1/1/2017
SpinrazaGCIT – effective 7/1/2021
Tecentriq – effective 7/1/2020
Tepezza – effective 7/1/2020
Tezspire – effective 3/23/2022
Tysabri – effective 7/1/2017
Ultomiris – effective 3/15/2019
Uplizna – effective 9/1/20
Viltepso – effective 11/10/20
Vimizim – effective 1/1/2020
Vpriv – effective 1/1/2020
Vyepti – effective 7/1/2020
Vyondys 53 – effective 3/1/2019
Xenpozyme – effective 12/2/2022
Xolair – effective 9/1/2020
Yervoy – effective 7/1/2020
ZolgensmaGCIT – effective 7/1/2019
ZyntegloGCIT – effective 1/1/2023
GCITProduct available for administration at Aetna Institutes® Gene Based, Cellular and Other Innovative Therapy (GCIT®) Designated Centers.
Aetna Institutes® GCIT Designated Centers
This policy applies to the following therapies administered by health care professionals:
- Orsini Pharmaceutical Services, LLC – Elk Grove Village, IL
- Children’s Hospital of Philadelphia – Philadelphia, PA
- The Children’s Hospital of Alabama – Birmingham, AL
- Children's Hospital Los Angeles – Los Angeles, CA
- University of Iowa Hospital and Clinics – Iowa City, IA
- Massachusetts Eye and Ear Infirmary – Boston, MA
- University of Michigan Medical Center – Kellogg Eye Center nn Arbor, MI
- Cincinnati Children's Hospital and Medical Center – Cincinnati, OH
- Oregon Health & Science University Hospital, Casey Eye Institute – Portland, OR
- Children's Hospital of Philadelphia – Philadelphia, PA
- Penn Presbyterian Medical Center (Scheie Eye Institute) – Philadelphia, PA
- Accredo Health Group, Inc – Memphis, TN
- St. Luke's Health Baylor College of Medicine Medical Center – Houston, TX
- Children’s Hospital of Philadelphia – Philadelphia, PA
- The Children's Hospital of Alabama – Birmingham, AL
- Banner University Medical Center Tucson Campus – Tucson, AZ
- Banner University Medical Center Phoenix Campus – Phoenix, AZ
- Diamond Children’s Hospital, part of Banner University Tucson Campus – Tucson, AZ
- Children's Hospital Los Angeles – Los Angeles, CA
- Lucile Packard Children's Hospital – Palo Alto, CA
- Rady Children's Hospital San Diego – San Diego, CA
- Stanford Medical Center – Stanford, CA
- Children's Hospital Colorado – Aurora, CO
- Connecticut Children's Medical Center – Farmington, CT
- Children's National Medical Center – Washington, DC
- MedStar Georgetown University Hospital – Washington, DC
- Nemours Children’s Hospital Delaware – Wilmington, DE
- Joe DiMaggio Children's Hospital – Hollywood, FL
- Memorial Hospital Regional – Hollywood, FL
- Nemours Children's Hospital – Orlando, FL
- Nicklaus Children's Hospital – Miami, FL
- St. Josephs Woman's Hospital (Baycare) – Tampa, FL
- Memorial Hospital Regional – Hollywood, FL
- Children's Healthcare of Atlanta, Scottish Rite Hospital – Atlanta, GA
- Children's Healthcare of Atlanta at Egleston – Atlanta, GA
- University of Iowa Hospital and Clinics – Iowa City, IA
- University of Kansas Medical Center – Kansas City, KS
- Boston Children's Hospital – Boston, MA
- Children's Hospital of Michigan – Detroit, MI
- Children's Hospital of Michigan – Grand Blanc, MI
- C S Mott Children's Hospital – Ann Arbor , MI
- University of Michigan Medical Center – Ann Arbor, MI
- Gillette Children's Specialty Healthcare – Saint Paul, MN
- The Children's Mercy Hospital – Kansas City, MO
- Children's Hospital and Medical Center – Omaha, NE
- Goryeb Children's Hospital at Morristown Medical Center – Morristown, NJ
- NYU Langone Tisch Hospital – New York, NY
- NYU Langone Hospital Brooklyn – Brooklyn, NY
- NYU Langone Hospital Long Island – Mineola, NY
- Cincinnati Children's Hospital and Medical Center – Cincinnati, OH
- Nationwide Children's Hospital – Columbus, OH
- Ohio State University Hospital – Columbus, OH
- The Children's Hospital at Oklahoma University Medical Center – Oklahoma City, OK
- Oregon Health & Science University Hospital, Doernbecher Children's Hospital – Portland, OR
- Children's Hospital of Philadelphia – Philadelphia, PA
- Milton Hershey Medical Center Pennsylvania State University – Hershey, PA
- Hospital of The University of Pennsylvania Health System – Philadelphia, PA
- Vanderbilt University Medical Center – Nashville, TN
- Monroe Carell, Jr. Children’s Hospital at Vanderbilt – Nashville, TN
- Cook Children's Medical Center – Fort Worth, TX
- Children's Medical Center of Dallas – Dallas, TX
- Primary Children's Hospital – Salt Lake City, UT
- Children's Hospital of The King's Daughters – Norfolk, VA
- Seattle Children's Hospital – Seattle, WA
- University of Wisconsin Hospital and Clinics – Madison, WI
- The Children's Hospital of Alabama – Birmingham, Al
- Children's Hospital Los Angeles – Los Angeles, CA
- Lucile Packard Children's Hospital – Palo Alto, CA
- Rady Children's Hospital San Diego – San Diego, CA
- Ronald Reagan UCLA Medical Center – Los Angeles, CA
- Stanford Medical Center – Stanford, CA
- Children's Hospital Colorado – Aurora, CO
- Connecticut Children's Medical Center – Farmington, CT
- Children's National Medical Center – Washington, DC
- Nemours Children’s Hospital Delaware – Wilmington, DE
- Jackson Memorial Hospital – Miami, FL
- Joe DiMaggio Children's Hospital – Hollywood, FL
- Nemours Children's Hospital – Orlando, FL
- Nicklaus Children's Hospital – Miami, FL
- St. Josephs Woman's Hospital (Baycare) – Tampa, FL
- Memorial Hospital Regional – Hollywood, FL
- Children's Healthcare of Atlanta at Scottish Rite – Atlanta, GA
- Children's Healthcare of Atlanta at Egleston – Atlanta, GA
- University of Iowa Hospital and Clinics – Iowa City, IA
- Ann and Robert H Lurie Children's Hospital of Chicago – Chicago, IL
- University of Kansas Medical Center – Kansas City, KS
- University of Kentucky Hospital – Lexington, KY
- Children's Hospital New Orleans – New Orleans, LA
- Massachusetts General Brigham – Boston, MA
- Children's Hospital of Michigan – Detroit, MI
- Children's Hospital of Michigan – Grand Blanc, MI
- C S Mott Children's Hospital – Ann Arbor, MI
- University of Michigan Medical Center – Ann Arbor, MI
- Gillette Children's Specialty Healthcare – Saint Paul, MN
- The Children's Mercy Hospital – Kansas City, MO
- Children's Hospital and Medical Center – Omaha, NE
- Goryeb Children's Hospital at Morristown Medical Center – Morristown, NJ
- Columbia University Medical Center – New York, NY
- University of Rochester Medical Center Health System – Strong Memorial Hospital – Rochester, NY
- NYU Langone Tisch Hospital – New York, NY
- NYU Langone Hospital Brooklyn – Brooklyn, NY
- NYU Langone Hospital Long Island – Mineola, NY
- NYU Langone Orthopedic Hospital – New York, NY
- Cincinnati Children's Hospital and Medical Center – Cincinnati, OH
- Nationwide Children's Hospital – Columbus, OH
- Akron Children's Hospital – Akron, OH
- Integris Southwest Medical Center – Oklahoma City, OK
- The Children's Hospital at Oklahoma University Medical Center – Oklahoma City, OK
- Oregon Health & Science University Hospital – Doernbecher Children's Hospital – Portland, OR
- Children's Hospital of Philadelphia – Philadelphia, PA
- Milton Hershey Medical Center Pennsylvania State University – Hershey, PA
- Vanderbilt University Medical Center – Nashville, TN
- Monroe Carell, Jr. Children’s Hospital at Vanderbilt – Nashville, TN
- Cook Children's Medical Center – Fort Worth, TX
- Children's Medical Center of Dallas – Dallas, TX
- Children's Hospital of The King's Daughters – Norfolk, VA
- Seattle Children's Hospital – Seattle, WA
- University of Wisconsin Hospital and Clinics – Madison, WI
- Children’s Hospital & Research Center dba Benioff Children’s Hospital Oakland – Oakland, CA
- Children’s Hospital of Philadelphia – Philadelphia, PA
For more information on Aetna Institutes® Gene Based, Cellular and Other Innovative Therapy (GCIT®) Designated Centers refer to our Aetna Institutes page.
Criteria for medical necessity
- The member is new to therapy or reinitiating therapy after not being on therapy for at least 6 months. For Xolair only, the member is new to therapy or reinitiating therapy after not being on therapy for at least 3 months.
- The member is switching to a product that he/she has not received before.*
- The member has experienced a gap in therapy.**
*Applies only to IVIG, infliximab and alpha-1-anti-trypsin products.
**Applies only to IVIG, Tysabri, and infliximab products.
The member has experienced an adverse reaction that did not respond to conventional interventions (e.g., acetaminophen, steroids, diphenhydramine, fluids or other pre-medications) or a severe adverse event (anaphylaxis, anaphylactoid reactions, myocardial infarction, thromboembolism, or seizures) during or immediately after administration.
- The member either has immunoglobulin A (IgA) deficiency with anti-IgA antibodies***or has developed anti-drug antibodies† which increases the risk for infusion related reactions.
- The member is medically unstable (e.g., respiratory, cardiovascular, or renal conditions).
- The member has severe venous access issues that require the use of a special intervention.††
- The member has significant behavioral issues and/or physical or cognitive impairment that would impact the safety of the administration AND the patient does not have access to a caregiver.
- For members receiving an immune checkpoint inhibitor (Bavencio, Imfinzi, Jemperli, Keytruda, Libtayo, Opdivo, Opdualag, Tecentriq, and Yervoy), ANY of the following additional criteria also apply:
- The member is within the initial 6 months of starting therapy;
- The member is continuing on a maintenance regimen that includes provider administered combination chemotherapy including but not limited to: i. Tecentriq used in combination with bevacizumab for non-small cell lung cancer (NSCLC); ii. Tecentriq used in combination with paclitaxel protein-bound for breast cancer; iii. Keytruda in combination with pemetrexed for NSCLC;
- The member is experiencing severe toxicity requiring continuous monitoring (e.g., Grade 2-4 bullous dermatitis, transaminitis, pneumonitis, Stevens-Johnson syndrome, acute pancreatitis, primary adrenal insufficiency aseptic meningitis, encephalitis, transverse myelitis, myocarditis, pericarditis, arrhythmias, impaired ventricular function, conduction abnormalities).
***Applies only to IVIG, HyQvia, Alpha 1 proteinase inhibitors.
†Applies only to Tysabri, Infliximab, Elaprase, Kanuma, Aldurazyme, Cerezyme, Fabrazyme, Lumizyme, Nexviazyme, and Xenpozyme.
††Does not apply to drugs administered by subcutaneous injection.
The following information is necessary to initiate the site of care prior authorization review (where applicable):
- Medical records supporting the member has experienced an adverse reaction that did not respond to conventional interventions or a severe adverse event during or immediately after administration
- Medical records supporting the member has IgA antibodies or has developed anti-drug antibodies
- Medical records supporting the member is medically unstable
- Medical records supporting the member has severe venous access issues that require specialized interventions only available in the outpatient hospital setting
- Medical records supporting the member has behavioral issues and/or physical or cognitive impairment and no access to a caregiver
- Medical records supporting the member is receiving provider administered combination chemotherapy
For situations where administration of the medication does not meet the criteria for outpatient hospital administration, coverage for the medication is provided when administered in alternative sites such as physician office, home infusion or ambulatory care.
|
Indication |
Days allowed |
---|---|---|
Actemra |
Rheumatoid arthritis (RA) only |
99 days |
Actemra |
Polyarticular Juvenile Idiopathic Arthritis(PJIA) only |
99 days |
Actemra |
Systemic Juvenile Idiopathic Arthirits (SJIA) only |
50 days |
Actemra |
Castleman's disease |
50 days |
Actemra |
Immunotherapy-related inflammatory arthritis only |
99 days |
Aldurazyme |
Mucopolysaccharidosis I |
54 days |
Elaprase |
Hunter syndrome |
54 days |
Fabrazyme |
Fabry disease |
106 days |
Infliximab |
Takayasu only |
85 days |
Kanuma |
LAL deficiency |
50 days |
Lumizyme |
Pompe disease |
106 days |
Mepsveii |
Mucopolysacaridosis VII |
50 days |
Naglazyme |
Mucopolysacaridosis VI |
54 days |
Nexviazyme |
Pompe disease |
106 days |
Oxlumo |
Primary hyperoxaluria type I |
60 days |
Vimizim |
Mucopolysacaridosis IVA |
82 days |
Vpriv |
Gaucher disease type I |
50 days |
Vyepti |
Migraine prevention |
50 days |
Xolair |
Asthma, chronic idiopathic urticaria |
60 days |
Immune Checkpoint Inhibitors (Bavencio, Imfinzi, Jemperli, Keytruda, Libtayo, Opdivo, Opdualag, Tecentriq, and Yervoy) |
All indications |
6-month initial authorization, then up to 45 day renewal |
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Medication billing procedure codes
Applicable codes
Actemra
Jcode: J3262
NDCs:
Adakveo
Jcode: J0791
NDCs:
Aduhelm
Jcode: J0172
NDCs:
Aldurazyme
Jcode: J1931
NDCs:
Alpha 1 proteinase inhibitor (human)
Jcode: J0256, S9346
NDCs:
Amondys 45
Jcode: J1426
NDCs:
Amvuttra
Jcode: J3490, J9999
NDCs: 71336-1003-01
Avsola
Jcode: Q5121
NDCs:
Bavencio
Jcode: J9023
NDCs:
Benlysta
Jcode: J0490
NDCs:
Bivigam
Jcode: J1556
NDCs:
Briumvi
Jcode: J3590
NDCs:
Cerezyme
Jcode: J1786
NDCs:
Cinqair
Jcode: J2786
NDCs:
Cinryze
Jcode: J0598
NDCs:
Crysvita
Jcode: J0584
NDCs:
Cuvitru
Jcode: J1555
NDCs:
Elaprase
Jcode: J1743
NDCs:
Elelyso
Jcode: J3060
NDCs:
Enjaymo
Jcode: J1302
NDCs:
Entyvio
Jcode: J3380
NDCs:
Evkeeza
Jcode: J1305
NDCs:
Exondys 51
Jcode: J1428
NDCs:
Fabrazyme
Jcode: J0180
NDCs:
Fasenra
Jcode: J0517
NDCs:
Flebogamma/Flebogamma dif (immune globulin)
Jcode: J1572
NDCs:
Gamma globulin
Jcode: J1460, J1560
NDCs:
Gammagard liquid
Jcode: J1569
NDCs:
Gammaplex
Jcode: J1557
NDCs:
Gamunex-c/Gammaked
Jcode: J1561
NDCs:
Givlaari
Jcode: J0223
NDCs:
Hemgenix
Jcode: J3590
NDCs:
Hizentra
Jcode: J1559
NDCs:
Hyqvia
Jcode: J1575
NDCs:
Imfinzi
Jcode: J9173
NDCs:
Immune globulin
Jcode: J1566, J1599
NDCs:
Inflectra (infliximab)
Jcode: Q5103, J1745
NDCs:
Jempreli
Jcode: J9272
NDCs:
Kanuma
Jcode: J2840
NDCs:
Keytruda
Jcode: J9271
NDCs:
Lemtrada
Jcode: J0202
NDCs:
Leqembi
Jcode: J3590
NDCs:
Libtayo
Jcode: J9119
NDCs:
Lumizyme
Jcode: J0220, J0221
NDCs:
Luxturna
Jcode: J3398
NDCs:
Mepsveii
Jcode: J3397
NDCs:
Naglazyme
Jcode: J1458
NDCs:
Nexviazyme
Jcode: J0219
NDCs:
Nucala
Jcode: J2182
NDCs:
Ocrevus
Jcode: J2350
NDCs:
Octagam
Jcode: J1568
NDCs:
Onpattro
Jcode: J0222
NDCs:
Opdivo
Jcode: J9299
NDCs:
Opdualag
Jcode: J9298
NDCs:
Orencia
Jcode: J0129
NDCs:
Oxlumo
Jcode: J0224
NDCs:
Privigen
Jcode: J1459
NDCs:
Radicava
Jcode: J1301
NDCs:
Remicade
Jcode: J1745
NDCs:
Renflexis
Jcode: Q5104
NDCs:
Saphnelo
Jcode: J0491
NDCs:
Skysona
Jcode: J3590
NDCs:
Simponi
Jcode: J1602
NDCs:
Soliris
Jcode: J1300
NDCs:
Spinraza
Jcode: J2326
NDCs:
Tecentriq
Jcode: J9022
NDCs:
Tepezza
Jcode: J3241
NDCs:
Tezspire
Jcode: J2356
NDCs:
Tysabri
Jcode: J2323
NDCs:
Ultomiris
Jcode: J1303
NDCs:
Uplizna
Jcode: J1823
NDCs:
Viltepso
Jcode: J1427
NDCs:
Vimizim
Jcode: J1322
NDCs:
Vpriv
Jcode: J3385
NDCs:
Vyepti
Jcode: J3032
NDCs:
Vyondys 53
Jcode: J1429
NDCs:
Xenpozyme
Jcode: J3590
NDCs: 58468-0050-01
Xolair
Jcode: J2357
NDCs:
Yervoy
Jcode: J9228
NDCs:
Zolgensma
Jcode: J3399
NDCs:
Zynteglo
Jcode: J3590
NDCs:
References
Actemra [prescribing information]. South San Francisco, CA: Genentech, Inc.; December 2022.
Adakveo [prescribing information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; July 2021.
Aduhelm [prescribing information]. Cambridge, MA: Biogen; April 2022.
Aldurazyme [prescribing information]. Novato, CA: BioMarin Pharmaceutical Inc.; December 2019.
American Academy of Allergy, Asthma and Immunology. Guidelines for the Site of Care for Administration of IGIV Therapy. December 2011.
Amondys 45 [package insert]. Cambridge, MA: Sarepta Therapeutics; February 2021.
Amvuttra [package insert]. Cambridge, MA: Alnylam Pharmaceuticals, Inc.; June 2022.
Aralast NP [package insert]. Lexington, MA: Baxalta US Inc.; December 2018.
Asceniv [prescribing information.] Kankakee, IL: CSL Behring LLC; April 2019.
Avsola [prescribing information]. Thousand Oaks, CA: Amgen Inc.; September 2021.
Bavencio [prescribing information]. Rockland, MA: EMD Serono, Inc; November 2020.
Benlysta [prescribing information]. Research Triangle Park, NC: GlaxoSmithKline; July 2022.
Bivigam [prescribing information]. Boca Raton, FL: Biotest Pharmaceuticals Corporation; July 2019.
Bonilla FA. Intravenous immunoglobulin: adverse reactions and management. J Allergy Clin Immunol. 2008;122(6):1238-1239.
Briumvi [prescribing information]. Morrisville, NC: TG Therapeutics, Inc.; December 2022.
Cerezyme [prescribing information]. Cambridge, MA: Genzyme Corporation.; December 2021.
Cinqair [prescribing information]. Frazer, PA: Teva Respiratory, LLC; February 2020.
Cinryze [prescribing information]. Lexington, MA: Shire ViroPharma Biologics Inc.; January 2021.
Crysvita [prescribing information]. Novato, CA: Ultragenyx Pharmaceutical Inc; June 2020.
Cutaquig [package insert]. Hoboken, NJ: Octapharma USA Inc; October 2021.
Cuvitru [package insert]. Lexington, MA: Baxalta USA Inc.; September 2021.
Elaprase [prescribing information]. Lexington, MA: Shire Human Genetic Therapies, Inc.; September 2021.
Elelyso [prescribing information]. NY, NY: Pfizer Inc.; August 2022.
Enjaymo [package insert]. Waltham, MA: Bioverativ USA Inc Inc.; February 2022.
Entyvio [prescribing information]. Deerfield, IL: Takeda Pharmaceuticals America, Inc.; June 2022.
Evkeeza [prescribing information]. Tarrytown, NY: Regeneron Pharmaceuticals Inc; February 2021.
Exondys 51 [prescribing information]. Cambridge, MA: Sarepta Therapeutics, Inc.; January 2022.
Fabrazyme [prescribing information]. Cambridge, MA: Genzyme Corporation.; March 2021.
Fasenra [prescribing information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; February 2021.
Flebogamma 10% DIF [prescribing information]. Barcelona, Spain: Instituto Grifols, SA; November 2019.
Flebogamma 5% DIF [prescribing information]. Barcelona, Spain: Instituto Grifols, SA; November 2019.
Gammagard Liquid [prescribing information]. Lexington, MA: Baxalta US Inc; March 2021.
Gammagard S/D IgA less than 1 mcg/mL [package insert]. Lexington, MA: Baxalta US Inc; March 2021.
Gammaked [package insert]. Research Triangle Park, NC: Grifols Therapeutics Inc.; January 2020.
Gammaplex 5% [package insert]. Durham, NC: Bio Products Laboratory Inc; September 2019.
Gammaplex 10% [package insert]. Durham, NC: Bio Products Laboratory Inc; October 2019.
Gamunex-C [package insert]. Research Triangle Park, NC: Grifols Therapeutics Inc.; January 2020.
Givlaari [prescribing information]. Cambridge, MA: Alnylam Pharmaceuticals.; January 2022.
Glassia [package insert]. Lexington, MA: Baxter US Inc.; March 2022.
Hemgenix [package insert]. King of Prussia, PA: CSL Behring LLC; November 2022.
Hizentra [package insert]. Kankakee, IL: CSL Behring LLC; April 2022.
HyQvia [package insert]. Lexington, MA: Baxalta USA Inc.; March 2021.
Imfinzi [prescribing information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; February 2021.
Inflectra [prescribing information]. Lake Forest, IL: Celltrion, Inc.; August 2020.
Jemperli [prescribing information]. Philadelphia, PA: GlaxoSmithKline LLC; April 2022.
Kanuma [prescribing information]. Cheshire, CT: Alexion Pharmaceuticals Inc.; November 2021.
Katzberg H, Rasutis V, Bril V Home iVIG for CIDP: A Focus on Patient Centred Care Can J Neurol Sci. 2013; 40: 384-388.
Keytruda [prescribing information]. Whitehouse Station, NJ: Merck & Co., Inc.; June 2022.
Lemtrada [prescribing information]. Cambridge, MA: Genzyme Corp.; January 2022.
Leqembi [prescribing information]. Nutley, NJ: Eisai Inc.; January 2023.
Libtayo [prescribing information]. Tarrytown, NY: Regeneron Pharmaceuticals, Inc.; November 2022.
Lumizyme [prescribing information]. Cambridge, MA: Genzyme Corporation; May 2022.
Luxturna [prescribing information]. Philadelphia, PA: Spark Therapeutics, Inc.; December 2019.
MCG Care Guidelines, 19th Edition, 2015, Home Infusion Therapy: CMT: CMT-0009
Mepsevii [prescribing information]. Novato, CA: Ultragenyx Pharmaceutical Inc.; December 2020.
Naglazyme [prescribing information]. Novato, CA: BioMarin Pharmaceutical Inc; December 2019.
Nexviazyme [prescribing information]. Cambridge, MA: Genzyme Corporation; August 2021.
Nucala [package insert]. Research Triangle Park, NC: GlaxoSmithKline, Inc.; January 2022.
Ocrevus [prescribing information]. Genentech, Inc. South San Francisco, CA.; March 2021.
Octagam 10% [package insert]. Hoboken, NJ: Octapharma USA, Inc.; February 2020.
Octagam 5% [package insert]. Hoboken, NJ: Octapharma USA, Inc.; July 2021.
Onpattro (patisiran) [prescribing Information]. Alnylam Pharmaceuticals, Inc. May 2021.
Opdivo [prescribing information]. Princeton, NJ: Bristol-Myers Squibb Company; May 2022.
Opdualag [package insert]. Princeton, NJ: Bristol-Myers Squibb Company; March 2022.
Orencia [prescribing information]. Princeton, NJ: Bristol-Myers Squibb Company; December 2021.
Oxlumo [prescribing information]. Cambridge, MA: Alnylam Pharmaceuticals, Inc; October 2022.
Panzyga [package insert]. Lingolsheim, France : Octapharma SAS, Inc; February 2021.
Privigen [package insert]. Bern, Switzerland: CSL Behring AG; March 2022.
Prolastin-C [package insert]. Research Triangle Park, NC: Grifols Therapeutics Inc.; May 2020.
Radicava [prescribing information]. Jersey City, NJ: MT Pharma America, Inc.; March 2021.
Remicade [prescribing information]. Horsham, PA: Janssen Biotech, Inc.; October 2021.
Renflexis [prescribing information]. Kenilworth, NJ: Merck & Co., Inc.; January 2022.
Rigas M, Tandan R, Sterling R. Safety of Liquid Intravenous Immunoglobulin for Neuroimmunologic Disorders in the Home Setting: A Retrospective Analysis of 1085 Infusions. J Clin Neuromusc Dis 2008; 10:52-55
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